Anti-VAChT pAb

The purified Anti-VAChT (Vesicular Acetylcholine Transporter) pAb is raised in goats against a peptide (CSPPGPFDGCEDDYNYYSRS) corresponding to amino acids 511–530 of the carboxy terminus of the cloned rat VAChT. It is a novel tool to identify functional cholinergic neurons in the central and peripheral nervous system where the antibody stains fibers and neuronal cell bodies. This antibody has application for the study of the pathophysiology of neurodegenerative diseases involving the cholinergic system and for mapping cholinergic neurons in the nervous system.

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The purified Anti-VAChT (Vesicular Acetylcholine Transporter) pAb is raised in goats against a peptide (CSPPGPFDGCEDDYNYYSRS) corresponding to amino acids 511–530 of the carboxy terminus of the cloned rat VAChT. It is a novel tool to identify functional cholinergic neurons in the central and peripheral nervous system where the antibody stains fibers and neuronal cell bodies. This antibody has application for the study of the pathophysiology of neurodegenerative diseases involving the cholinergic system and for mapping cholinergic neurons in the nervous system.

Features - Benefits

• Immunogen: Carboxy-terminal peptide sequence 511–530 corresponding to cloned rat VAChT protein.
• Antibody Form: Purified goat polyclonal IgG; 0.5mg/ml in PBS containing no preservatives.
• Specificity: Cross-reacts with VAChT in rat and mouse, but not in human, guinea pig, rabbit or cat.

Applications

(Suggested working dilution)

• Immunohistochemistry (1:500).

For more information, see the Protocols & Applications Guide.

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